Persistent reactivable latent herpes simplex virus infection in trigeminal ganglia of mice treated with antiviral drugs
- 1 March 1981
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 69 (1), 43-48
- https://doi.org/10.1007/bf01315264
Abstract
Latent reactivable infection was established with HSV in mouse trigeminal ganglion. A number of antiviral drugs (IUDR, acycloguanosine, Ara-A, PAA and PFA), effective against acute CNS infection with HSV, failed to influence the latent infection once established. Neither lipophilic properties of PFA-derivatives nor the combination of Ara-A and acyloguanosine improved the drug-effects on HSV latency.This publication has 22 references indexed in Scilit:
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