Reports concerning drug therapy of patients with convulsive disorders deal for the most part with the results of newer anticonvulsant agents. Each new anticonvulsant is introduced with claims of various improvements over its predecessor. These claims of improvements vary from better control of a particular type of seizure to greater over-all control of all seizures and at times decreased toxic manifestations. The initial enthusiasm is often modified as long-term administration of the drug to large groups of patients allows the many variable factors inherent in this illness, as well as the limitations of the drug itself, to become apparent. Though this fact is recognized, there are few reports in the literature that give the results of prolonged therapy in a large number of cases. Bromides, which have been used for almost 100 years, have been the subject of only a few reports that give results of long-term administration to a