AN ATTEMPT AT DEMONSTRATION OF AN INDOLIC SUBSTANCE IN ENTEROCHROMAFFIN CELLS BY USE OF HYPERTONIC SUCROSE SOLUTION

Abstract

It was concluded that no additional indole reactive material was conserved in guinea pig or mouse duodenum by use of hypertonic sucrose before or during formaldehyde fixation; that the enterochromaffin cells could not by this procedure be shown to contain an indole reactive substance; that soaking in 0.88 [image] sucrose even for 30 minutes partially disrupts and dissolves the proteins of the Paneth cell granules, and that with longer exposures the zymogen granules of the pancreatic acini and of the peptic glands undergo similar partial solution.