Changes in Rate of Intestinal Absorption of Sodium Chloride Solutions

Abstract

Absorption of distilled water, NaCl solutions and 1.0% glucose solution was studied in acute experiments in dogs anesthetized with sodium pentobarbital. A reduction in rate of absorption in consecutive 10-minute periods was observed for distilled water and solutions of 0.2% NaCl, 0.9% NaCl and 1.0% glucose. The degree of change in rate of absorption is inversely proportional to the concentration of test solution for distilled water, 0.2% NaCl, 0.9% NaCl and 1.0% NaCl. The inhibiting effect of hypotonic NaCl solutions on absorption is of local origin and is reversed in part by 2.0% NaCl solution.