The Effect of Schistosoma Mansoni Infections on Liver Function in Mice
- 1 November 1955
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 4 (6), 1072-1079
- https://doi.org/10.4269/ajtmh.1955.4.1072
Abstract
Summary The livers of mice infected with S. mansoni showed a reduced ability to oxidize succinic acid despite the fact that endogenous respiration was little affected. The effect on the succinoxidase activity is possibly, in part, attributable to the incorporation within the liver of extra-hepatic tissues, but the existence of a toxic influence by the infection was not ignored. The total nitrogen of infected liver was slightly higher than that of normal liver and an increase in liver collagen accompanied the present infections. No effect of preliminary extracts of infected liver and adult worm were obtained on the succinoxidase system of normal mouse liver. Tyrosinase activity of mouse liver was unaffected by the infection but the glycolytic mechanism was somewhat reduced in activity.Keywords
This publication has 4 references indexed in Scilit:
- The Effect of Schistosoma Mansoni Infections on Liver Function in MiceThe American Journal of Tropical Medicine and Hygiene, 1954
- The Histopathology of Experimental SchistosomiasisThe American Journal of Tropical Medicine and Hygiene, 1953
- An Efficient Method for Exposure of Mice to Cercariae of Schistosoma mansoniJournal of Parasitology, 1952
- Diabetes Mellitus and Pylephlebitic Abscess of the Liver Resulting from Schistosoma Mansoni InfestationThe American Journal of Tropical Medicine, 1950