Peroxisomal oxidation of lignoceric acid in rat brain
- 1 February 1986
- journal article
- research article
- Published by Springer Nature in Neurochemical Research
- Vol. 11 (2), 281-289
- https://doi.org/10.1007/bf00967975
Abstract
The oxidation of [1-14C]lignoceric acid was studied in different subcellular fractions of rat brain. The highest specific activity for oxidation of [1-14C]lignoceric acid to acetate was observed in the light mitochondrial fraction. The oxidation of [1-14C]lignoceric acid had an absolute requirement for CoASH and ATP. It was stimulated by NAD and FAD by 400 and 280 percent, respectively, whereas addition of carnitine and KCN had no effect. These properties suggest that in brain [1-14C]lignoceric acid is oxidized in peroxisomes.This publication has 24 references indexed in Scilit:
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