Hepatocellular carcinoma in a child with familial Russell‐Silver syndrome
- 1 December 1988
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 31 (4), 909-914
- https://doi.org/10.1002/ajmg.1320310425
Abstract
We describe a 4‐year‐old boy with Russell‐Silver syndrome (RSS) found to have hepatocellular carcinoma. The brother of this child also had manifestations of RSS. This is the third malignancy and the first hepatocellular carcinoma described in a patient with RSS. The coexistence of hepatocellular carcinoma and RSS may be completely fortuitous; however, the known association of liver cancer with growth abnormality and hemihypertrophy, findings also present in RSS, suggest that these disorders may be related.Keywords
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