Evidence for regulation of gluconeogenesis by the fructose phosphotransferase system in Salmonella typhimurium
Open Access
- 1 February 1987
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 169 (2), 897-899
- https://doi.org/10.1128/jb.169.2.897-899.1987
Abstract
A genetic locus designated fruR, previously mapped to min 3 on the Salmonella typhimurium chromosome, gave rise to constitutive expression of the fructose (fru) regulon and pleiotropically prevented growth on all Krebs cycle intermediates. Regulatory effects of fruR were independent of cyclic AMP and its receptor protein and did not prevent uptake of Krebs cycle intermediates. Instead, the phosphotransferase system appeared to regulate gluconeogenesis by controlling the activities of phosphoenolpyruvate carboxykinase and phosphoenolpyruvate synthase.This publication has 28 references indexed in Scilit:
- Phosphoenolpyruvate:carbohydrate phosphotransferase system of bacteria.1985
- Mechanisms of Carbohydrate TransportPublished by Elsevier ,1985
- Evidence for the evolutionary relatedness of the proteins of the bacterial phosphoenolpyruvate:Sugar phosphotransferase systemJournal of Cellular Biochemistry, 1985
- The kinetic properties of phosphoenolpyruvate carboxykinase of Escherichia coliCanadian Journal of Biochemistry, 1980
- Sugar transport. Properties of mutant bacteria defective in proteins of the phosphoenolpyruvate: sugar phosphotransferase system.Journal of Biological Chemistry, 1976
- Coordinate regulation of adenylate cyclase and carbohydrate permeases by the phosphoenolpyruvate:sugar phosphotransferase system in Salmonella typhimurium.Journal of Biological Chemistry, 1975
- Insensitivity of D-amino acid dehydrogenase synthesis to catabolic repression in dadR mutants of Salmonella typhimuriumMolecular Genetics and Genomics, 1975
- [48] Phosphoenolpyruvate synthetasePublished by Elsevier ,1969
- The Phosphoenolpyruvate-initiated Pathway of Fructose Metabolism in Escherichia coliJournal of Biological Chemistry, 1968
- Location on the chromosome of Escherichia coli of a gene specifying phosphopyruvate synthase activityBiochimica et Biophysica Acta (BBA) - General Subjects, 1967