Transferability of macrolide, lincomycin, and streptogramin resistances between group A, B, and D streptococci, Streptococcus pneumoniae, and Staphylococcus aureus

Abstract
The transferability of plasmid pRI405 between various streptococci of groups A, B and D, S. pneumoniae, and S. aureus is described. pRI405 originated from S. faecalis and encodes for resistance to macrolides, lincomycin and streptogramin B (MLS resistance). The host range of the well-documented streptococcal plasmid pAM.beta.1 was similar to that of pRI405. Cleavage with restriction enzymes suggests that pRI405 belongs to a related family of MLS resistance plasmids.