The new stem cell biology: something for everyone
Open Access
- 1 April 2003
- journal article
- review article
- Published by BMJ in Molecular Pathology
- Vol. 56 (2), 86-96
- https://doi.org/10.1136/mp.56.2.86
Abstract
The ability of multipotential adult stem cells to cross lineage boundaries (transdifferentiate) is currently causing heated debate in the scientific press. The proponents see adult stem cells as an attractive alternative to the use of embryonic stem cells in regenerative medicine (the treatment of diabetes, Parkinson’s disease, etc). However, opponents have questioned the very existence of the process, claiming that cell fusion is responsible for the phenomenon. This review sets out to provide a critical evaluation of the current literature in the adult stem cell field.Keywords
This publication has 90 references indexed in Scilit:
- RETRACTED ARTICLE: Pluripotency of mesenchymal stem cells derived from adult marrowNature, 2002
- Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem CellCell, 2001
- Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone MarrowScience, 2000
- Mammalian Neural Stem CellsScience, 2000
- Origins of circulating endothelial cells and endothelial outgrowth from bloodJournal of Clinical Investigation, 2000
- Mechanisms of cell injury and death in cholestasis and hepatoprotection by ursodeoxycholic acidJournal of Hepatology, 2000
- Dystrophin expression in the mdx mouse restored by stem cell transplantationNature, 1999
- Number and Proliferation of Clara Cells in Normal Human Airway EpitheliumAmerican Journal of Respiratory and Critical Care Medicine, 1999
- Embryonic Stem Cell Lines Derived from Human BlastocystsScience, 1998
- Pluripotential liver stem cells: facultative stem cells located in the biliary treeCell Proliferation, 1996