Conformational isomers and ring inversion of neolinderalactone, a ten-membered-ring furanosesquiterpene

Abstract

The ¹H n.m.r. and c.d. spectra of two conformational isomers of neolinderalactone (I) at various temperatures have been examined to determine their conformations, their Gibbs' free energy difference, and the potential barrier to inversion of the ten-membered ring.