How the olfactory system makes sense of scents
Top Cited Papers
- 1 September 2001
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 413 (6852), 211-218
- https://doi.org/10.1038/35093026
Abstract
The human nose is often considered something of a luxury, but in the rest of the animal world, from bacteria to mammals, detecting chemicals in the environment has been critical to the successful organism. An indication of the importance of olfactory systems is the significant proportion - as much as 4% - of the genomes of many higher eukaryotes that is devoted to encoding the proteins of smell. Growing interest in the detection of diverse compounds at single-molecule levels has made the olfactory system an important system for biological modelling.Keywords
This publication has 64 references indexed in Scilit:
- The Genomic Structure of Human Olfactory Receptor GenesGenomics, 2000
- Crystal Structure of Rhodopsin: A G Protein-Coupled ReceptorScience, 2000
- The Molecular Architecture of Odor and Pheromone Sensing in MammalsCell, 2000
- Seven-Transmembrane Proteins as Odorant and Chemosensory ReceptorsScience, 1999
- The variable and conserved interfaces of modeled olfactory receptor proteinsProtein Science, 1999
- Identification of Ligands for Olfactory Receptors by Functional Expression of a Receptor LibraryCell, 1998
- MECHANISMS OF OLFACTORY DISCRIMINATION: Converging Evidence for Common Principles Across PhylaAnnual Review of Neuroscience, 1997
- Visualizing an Olfactory Sensory MapCell, 1996
- A novel multigene family may encode odorant receptors: A molecular basis for odor recognitionCell, 1991
- Chimeric α 2 -,β 2 -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding SpecificityScience, 1988