BEHAVIOURAL ACTION OF ANDROGEN IN THE DOVE: EFFECTS OF LONG-TERM CASTRATION ON RESPONSE SPECIFICITY AND BRAIN AROMATIZATION
- 1 August 1981
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 90 (2), 167-178
- https://doi.org/10.1677/joe.0.0900167
Abstract
Differences in the effectiveness of oestradiol-17β and testosterone on male courtship and vocal behaviour were examined in long-term castrated doves. Nest-orientated behaviour was restored by intramuscular injection of oestradiol-17β. Testosterone was effective in restoring aggressive courtship and vocal behaviour, but not for the nest-orientated behaviour. The effects of these hormones were separable, therefore, under conditions of prolonged androgen deficit, suggesting differences in their specificity of action. In-vitro assay of brain enzyme activity indicated that aromatization of testosterone to oestradiol-17β occurred in the preoptic area of long-term castrated doves. Preoptic aromatase activity of long- and short-term castrated doves did not differ. The ineffectiveness of testosterone in restoring nest-orientated behaviour in long-term castrated doves did not appear, therefore, to be due to a difference between the groups in the basal rate of testosterone aromatization in the preoptic area.This publication has 9 references indexed in Scilit:
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