CHANGES IN THE HYPOPHYSIS AND THE OVARIES OF RATS CHRONICALLY TREATED WITH AN ANTERIOR PITUITARY EXTRACT
- 1 September 1938
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 23 (3), 279-284
- https://doi.org/10.1210/endo-23-3-279
Abstract
Continuous treatment with a pig pituitary extract (method of prep. described) resulted in a transient increase in ovarian wt. due to the formation of many corpora lutea. The peak of increase was reached more rapidly in adult rats, but was more pronounced in immature rats. In hypophysectomized animals the peak was somewhat delayed. Then ovarian size retrogressed, and "signet ring" cells appeared in the hypophysis. The ovaries became resistant not only to gonadotropic action of the extract but also to implants of rat hypophysis.This publication has 3 references indexed in Scilit:
- QUANTITATIVE STUDIES ON THE REACTION OF THE ANTERIOR PITUITARIES OF IMMATURE FEMALE RATS TO EXTRACTS OF PREGNANCY URINE*Endocrinology, 1935
- ON THE EFFECT OF THE ANTERIOR PITUITARY-LIKE HORMONE ON THE OVARY OF THE HYPOPHYSECTOMIZED RATEndocrinology, 1933
- Experimental studies of the anterior pituitary. II. The occurrence of pregnancy cells in mice following continuous anterior-lobe administrationThe Anatomical Record, 1931