The purpose of the present work was to study the effects on the tissues of the so-called cutting and coagulating currents, in order to ascertain what specific differences in effects might exist between the two, if any, in the hope of determining the probable damage to the tissues and the rapidity of repair after operations with these currents. The specific effects on several types of tissues were investigated. Sections were made in the skin of the frog, rabbit and dog; various incisions were produced in skeletal and smooth muscle, and the type of tissue lesion was described. Some attempts were made to investigate the histology of blood vessel closure by means of electricity. The present interest in the employment of the so-called "electric cutting current" devolves on the hope and expectancy of attaining two primary technical advantages: 1. The production of a current which will section vascular tissues and organs