The conflict between in vitro release studies in human biorelevant media and the in vivo exposure in rats of the lipophilic compound fenofibrate
- 29 July 2011
- journal article
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 414 (1-2), 118-124
- https://doi.org/10.1016/j.ijpharm.2011.05.009
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Formulate-ability of ten compounds with different physicochemical profiles in SMEDDSEuropean Journal of Pharmaceutical Sciences, 2009
- Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An UpdatePharmaceutical Research, 2008
- Bioavailability of seocalcitol: III. Administration of lipid-based formulations to minipigs in the fasted and fed stateEuropean Journal of Pharmaceutical Sciences, 2007
- Bioavailability of seocalcitolEuropean Journal of Pharmaceutical Sciences, 2006
- Dissolution and Solubility Behavior of Fenofibrate in Sodium Lauryl Sulfate SolutionsDrug Development and Industrial Pharmacy, 2005
- Intestinal Lymphatic Transport of Halofantrine Occurs After Oral Administration of a Unit-Dose Lipid-Based Formulation to Fasted DogsPharmaceutical Research, 2003
- Anatomical and physiological parameters affecting gastrointestinal absorption in humans and ratsFood and Chemical Toxicology, 2001
- Effect of Short‐, Medium‐, and Long‐Chain Fatty Acid‐Based Vehicles on the Absolute Oral Bioavailability and Intestinal Lymphatic Transport of Halofantrine and Assessment of Mass Balance in Lymph‐Cannulated and Non‐cannulated RatsJournal of Pharmaceutical Sciences, 2000
- Lipid-Based Delivery Systems for Improving the Bioavailability and Lymphatic Transport of a Poorly Water-Soluble LTB4 InhibitorJournal of Pharmaceutical Sciences, 1998
- Absorption of a pharmacological dose of vitamin D3 from two different lipid vehicles in man: Comparison of peanut oil and a medium chain triglycerideBiopharmaceutics & Drug Disposition, 1990