Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci
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- 1 April 2001
- journal article
- Published by Springer Nature in Nature Genetics
- Vol. 27 (4), 372-373
- https://doi.org/10.1038/86867
Abstract
We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity.Keywords
This publication has 15 references indexed in Scilit:
- A major susceptibility locus for atopic dermatitis maps to chromosome 3q21Nature Genetics, 2000
- The alliance of genes and environment in asthma and allergyNature, 1999
- Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest SwedenEuropean Journal of Human Genetics, 1999
- Searching for Psoriasis Susceptibility Genes in Italy: Genome Scan and Evidence for a New Locus on Chromosome 1Journal of Investigative Dermatology, 1999
- Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseasesProceedings of the National Academy of Sciences, 1998
- Identification of a Major Susceptibility Locus on Chromosome 6p and Evidence for Further Disease Loci Revealed by a Two Stage Genome-Wide Search in PsoriasisHuman Molecular Genetics, 1997
- Evidence that a locus for familial psoriasis maps to chromosome 4qNature Genetics, 1996
- Gene for Familial Psoriasis Susceptibility Mapped to the Distal End of Human Chromosome 17qScience, 1994
- Atopic dermatitis: A genetic-epidemiologic study in a population-based twin sampleJournal of the American Academy of Dermatology, 1993
- Immunoglobulin E in DermatosesArchives of Dermatology, 1969