HEMOSTATIC FAILURE OF PROTHROMBIN COMPLEX CONCENTRATES DURING ELECTIVE DENTAL PROCEDURE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 42 (5), 1604-1606
Abstract
One hemophilia A patient with an inhibitor was exposed to a graded surgical procedure and treated with prothrombin complex concentrates (PCC). Hemostasis was not obtained until the inhibitor was neutralized and the patient''s factor VIII level was normal. This patient was presented to emphasize that PCC are not nearly as effective as once hoped in producing hemostasis in inhibitor patients. Major decisions should not be made presuming efficacy of these products in inhibitor patients.