Solid-phase gene assembly
- 1 August 1991
- journal article
- Published by Springer Nature in Nature
- Vol. 352 (6335), 548-549
- https://doi.org/10.1038/352548a0
Abstract
New technologies for multiple chemical synthesis of oligonucleotides and stepwise hybridization on a solid-phase support enable the rapid and cost-effective preparation of long duplex DNA regions. Will these new technologies usher in a new era in protein engineering?Keywords
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