Stability engineering of antibody single-chain Fv fragments
Top Cited Papers
- 1 February 2001
- journal article
- review article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 305 (5), 989-1010
- https://doi.org/10.1006/jmbi.2000.4265
Abstract
No abstract availableKeywords
This publication has 127 references indexed in Scilit:
- The scFv fragment of the antibody hu4d5-8: evidence for early premature domain interaction in refoldingJournal of Molecular Biology, 2001
- Intrabody construction and expression. II. A synthetic catalytic Fv fragmentJournal of Molecular Biology, 1999
- Intrabody construction and expression. I. The critical role of VL domain stabilityJournal of Molecular Biology, 1999
- Improved stability and yield of a Fv-toxin fusion protein by computer design and protein engineering of the FvJournal of Molecular Biology, 1998
- P22 tailspike folding mutants revisited: effects on the thermodynamic stability of the isolated β-helix domainJournal of Molecular Biology, 1998
- Antibody scFv fragments without disulfide bonds, made by molecular evolutionJournal of Molecular Biology, 1998
- Reduction in the amide hydrogen exchange rates of an anti-lysozyme Fv fragment due to formation of the Fv-Lysozyme complexJournal of Molecular Biology, 1997
- Stabilization of a recombinant Fv fragment bybase-loop interconnection and VH-VL permutationJournal of Molecular Biology, 1997
- Crystallization of Single-Chain Fv ProteinsJournal of Molecular Biology, 1993
- Replacing the complementarity-determining regions in a human antibody with those from a mouseNature, 1986