WHIPPLE'S DISEASE (INTESTINAL LIPODYSTROPHY): REVIEW OF THE LITERATURE AND REPORT OF A CASE SUCCESSFULLY TREATED WITH ADRENOCORTICOTROPIN (ACTH) AND CORTISONE
- 1 November 1954
- journal article
- review article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 41 (5), 1066-1075
- https://doi.org/10.7326/0003-4819-41-5-1066
Abstract
Cases (54) of this disease were reviewed, manifestations being abdominal distress, weight loss, diarrhea, arthralgia, generalized pigmentation and steatorrhea. Symptomatic remsission curred in the authors'' patient after a brief course of treatment and adrenocorticotropic hormone and cortisone. A brief discussion of pathogenesis presents the view that elevation of serum glycoproteins in this disease, presence of positive stain for glycoproteins in biopsied mesenteric lymph nodes using the periodic-acid Shiff technique, and clinical symptoms tend to incriminate intestinal lipodystrophy as being in the rheumatic group of diseases.Keywords
This publication has 8 references indexed in Scilit:
- A Possible Cause of Death in Whipple's DiseaseGastroenterology, 1952
- Intestinal Lipodystrophy (Whipple's Disease)New England Journal of Medicine, 1950
- The Tinctoral Demonstration of a Glycoprotein in Whipple's DiseaseExperimental Biology and Medicine, 1949
- IDIOPATHIC STEATORRHEA: WITH REPORT OF A CASE OF WHIPPLE'S DISEASEAnnals of Internal Medicine, 1948
- INTESTINAL LIPODYSTROPHY OF WHIPPLE - REPORT OF A CASE AND ANALYSIS OF THE LITERATURE1947
- MECANISMES ET CONSEQUENCES DE LACCUMULATION DES POUSSIERES DANS LES GAINES BRONCHIQUES ET ARTERIELLES AU COURS DES PNEUMOCONIOSES1947
- Mesenteric chyladenectasis with steatorrhœa and features of Addison's diseaseThe Journal of Pathology and Bacteriology, 1938
- Mesenteric chyladenectasis - Report of a case1937