Immunohistochemical localization of chondroitin sulfate and dermatan sulfate proteoglycan in human gingival connective tissue

Publisher Website
Google Scholar
Abstract
This study investigated the immunohistochemical localization of chondroitin sulfate (chondroitin, 4-sulfate and 6-sulfate) and dermatan sulfate proteoglycan (PG) in human gingival connective tissue, using monoclonal antibodies. Dermatan sulfate was found to be widespread in conective tissue, with an especially strong response shown in collagen fiber bundles under the epithelial basement membrane. Chondrotin 4-sulfate occurred widely in connective tissue but showed only a weak response. Chondrotin 6-sulfate was located in peripheral blood vessels. Chondroitin was not detected in gingival connective tissue.