Inhibition of Nuclear Translocation of Apoptosis-Inducing Factor Is an Essential Mechanism of the Neuroprotective Activity of Pigment Epithelium-Derived Factor in a Rat Model of Retinal Degeneration
- 1 November 2008
- journal article
- Published by Elsevier in The American Journal of Pathology
- Vol. 173 (5), 1326-1338
- https://doi.org/10.2353/ajpath.2008.080466
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Education, Culture, Sports, Science and Technology (16390118, 17689047, 19209012)
This publication has 57 references indexed in Scilit:
- HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in miceJournal of Clinical Investigation, 2008
- Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)Journal of Hepatology, 2007
- Critical Role of Calpain I in Mitochondrial Release of Apoptosis-Inducing Factor in Ischemic Neuronal InjuryJournal of Neuroscience, 2007
- Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitorsProceedings of the National Academy of Sciences, 2006
- Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosisThe EMBO Journal, 2006
- Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in durationProceedings of the National Academy of Sciences, 2006
- Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesisAmerican Journal of Ophthalmology, 2004
- Simian immunodeficiency virus-based lentivirus vector for retinal gene transfer: a preclinical safety study in adult ratsGene Therapy, 2003
- Caspase-independent photoreceptor apoptosis in vivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal developmentCell Death & Differentiation, 2002
- Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome c Release to the Point of Mitochondrial DepolarizationThe Journal of cell biology, 2000