NATURAL-HISTORY OF PAPILLARY LESIONS OF URINARY-BLADDER IN SCHISTOSOMIASIS

Abstract

Variable epithelial hyperplasia was observed in urinary bladder of 9 capuchin monkeys (Cebus apella) when examined at cystotomy 94-164 wk after infection with Schistosoma haematobium. These hosts were followed for 24 to 136 wk postcystotomy to determine the status of bladder lesions in relation to duration of infection and to ascertain whether lesion samples removed at cystotomy reestablished themselves in autologous and heterologous transfers. There was involution of urothelial hyperplasia in 8 of 9 animals and no evidence for establishment of transplanted bladder lesions.