Plasma pentobarbitone levels
- 1 October 1976
- journal article
- Published by Wiley in Anaesthesia
- Vol. 31 (8), 1032-1036
- https://doi.org/10.1111/j.1365-2044.1976.tb11940.x
Abstract
A simple and relatively quick method of estimating pentobarbitone in plasma samples is reported using an ether extraction and gas-liquid chromatography. Glutethimide was used as the internal standard and proved reliable. Reproducible results were obtained in plasma following 100 mg pentobarbitone given by mouth or intramuscular injection. Evaporation in a heating block at 37 degrees C and storage of samples at -20 degrees C prior to analysis is recommended.Keywords
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