Cell survival and radiation induced chromosome aberrations
- 1 December 1986
- journal article
- research article
- Published by Springer Nature in Radiation and Environmental Biophysics
- Vol. 25 (4), 243-251
- https://doi.org/10.1007/bf01214637
Abstract
Summary Existing mathematical formulations to predict the frequency of radiation induced chromosome aberrations in 2nd post-irradiation division are based on the Poisson distribution [3, 4]. Meanwhile several studies have shown that intercellular distributions exist, deviating from Poisson. In the present study a modified model was developed which permits the application of empirical distributions. Transmission and survival parameters of aberrations can be iteratively computed. A general formula was derived for the calculation of cell survival from 1st to 2nd division.Keywords
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