Secondary structure prediction for RNA binding domain in RNP proteins identifies βαβ as the main structural motif
- 6 November 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 257 (2), 373-376
- https://doi.org/10.1016/0014-5793(89)81575-3
Abstract
In eukaryotic cells transcript processing is strictly dependent upon binding of specific proteins. Nuclear RNA binding proteins share a common domain, which is involved in RNA binding. In order to characterize RNP-RNA interactions we have performed a secondary structure prediction based both on statistical algorithms and comparative analysis of different proteins. A high conservation for secondary structure propensity between different RNPs was observed.Keywords
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