Cure of intractable watery diarrhoea by excision of a vipoma
- 1 April 1978
- journal article
- case report
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 65 (4), 234-236
- https://doi.org/10.1002/bjs.1800650406
Abstract
A 56-year-old man suffered unexplained watery diarrhoea for 5 years which ultimately produced quadraparesis due to serve potassium depletion. All investigations were negative until demonstration of elevated plasma vasoactive intestinal peptide (VIP) indicated the presence of a vipoma. Removal of the VIP-producing tumour tissue–an adrenal ganglioneuroma–resulted in complete cure. Plasma VIP measurement is thus a valuable diagnostic screen in such cases and can be used to predict prognosis and to guide further therapy.Keywords
This publication has 8 references indexed in Scilit:
- Streptozocin-Treated Verner-Morrison SyndromeArchives of Internal Medicine, 1976
- POSSIBLE DUAL ROLE FOR VASOACTIVE INTESTINAL PEPTIDE AS GASTROINTESTINAL HORMONE AND NEUROTRANSMITTER SUBSTANCEThe Lancet, 1976
- VIP MEASUREMENT IN DISTINGUISHING VERNER‐MORRISON SYNDROME AND PSEUDO VERNER‐MORRISON SYNDROMEClinical Endocrinology, 1976
- Endocrine Pancreatic Islet Disease With DiarrheaArchives of Internal Medicine, 1974
- VASOACTIVE INTESTINAL PEPTIDE AND WATERY-DIARRHŒA SYNDROMEThe Lancet, 1973
- Recognition and management of the diarrheal syndrome caused by nonbeta islet cell tumors of the pancreasThe American Journal of Surgery, 1970
- Islet Cell Tumor of the Pancreas with Reversible Watery Diarrhea and AchlorhydriaGastroenterology, 1967
- Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemiaAmerican Journal Of Medicine, 1958