Abstract
Despite much journalistic hyperbole, the publication last year of nearly complete sequences of the human genome1,2 did not mean that the practice of medicine would be abruptly and radically transformed. Medicine has not been a gene-free art form in living memory — a knowledge of genetics has had an increasingly important role in medicine for over a century. Nor will it soon, if ever, become an impersonal, information-based science enabling every person to know from birth the ailments he or she will have and the perfect way to treat them.

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