A Preliminary Study of Photodynamic Therapy Using Verteporfin for Choroidal Neovascularization in Pathologic Myopia, Ocular Histoplasmosis Syndrome, Angioid Streaks, and Idiopathic Causes

Abstract

CHOROIDAL neovascularization (CNV) is a leading cause of loss of central vision in developed countries. Choroidal neovascularization disrupts the anatomy of the retinal pigment epithelium–photoreceptor complex, leaks serum and sometimes blood, and is often accompanied by irreversible scar formation that is associated with a loss of photoreceptors.^1,2 Choroidal neovascularization is encountered most often in patients with age-related macular degeneration (AMD), but also occurs as a consequence of other causes such as pathologic myopia, the ocular histoplasmosis syndrome, angioid streaks, or idiopathic causes.