BIOSYNTHESIS OF BACTERIAL LIPOPOLYSACCHARIDE, I. ENZYMATIC INCORPORATION OF GALACTOSE IN A MUTANT STRAIN OF SALMONELLA
Open Access
- 1 October 1962
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 48 (10), 1831-1838
- https://doi.org/10.1073/pnas.48.10.1831
Abstract
An enyme system, UDP-galactose-4-epimerase, is described which is derived from a mutant strain of S. typhimurium and appears to be involved in the biosynthesis of the cell-wall lipopolysaccharide. The enzyme system was stimulated by Mg++and Mn++ions, and inhibited by relatively high levels of uracil nucleotides. It is suspected that the product of the UDP-galactose trans-ferase contains galactose bound to the glucose-heptose-phosphate poly-saccharide.Keywords
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