Serum Lactic Dehydrogenase and Ribonuclease in the Diagnosis of Malignant Tumours in Children

Abstract
Serum lactic dehydrogenase (SLD) activity rises up to 3 times normal values in almost 100% of cases of malignant tumors in children. SLD level increases in every case of disseminated cancer. Hence it can be a factor of importance in the prognosis and diagnosis of neoplastic diseases in children, especially in the age-group 0-2 years. Ribonuclease activity in serum does not give as distinct a picture of neoplastic diseases as SLD does.