The presence of β‐adrenoceptors in the guinea‐pig seminal vesicle
Open Access
- 1 May 1972
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 45 (1), 21-28
- https://doi.org/10.1111/j.1476-5381.1972.tb09572.x
Abstract
1 . The preparation of longitudinal smooth muscle strips from guinea-pig seminal vesicles is described. 2 . Isoprenaline and salbutamol inhibited contractions produced by parasympathomimetic agents. 3 . The inhibitory action of isoprenaline was blocked by low concentrations of propranolol and butoxamine. It was concluded that β2-adrenoceptors were present in the tissue. 4 . The inhibitory action of isoprenaline was not apparent when adrenaline, noradrenaline, hypogastric nerve or transmural stimulation were used to contract the tissue.Keywords
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