Acute Histopathologic Inner Ear Changes in Deafness Due to Neomycin: A Case Report

Abstract
A case presentation of a patient receiving 8 gm of neomycin intramuscularly in preparation for surgery is presented. Acute renal failure and total deafness followed this injection and the temporal bones were removed on the seventeenth day postinjection. Histological findings showed inner and outer hair cell degeneration and a normal spiral ganglion count. There were some changes in the stria vascularis which were noted in the basal turn.