Incorporation in Vitro of Precursor Into Protein and RNA of Rat Adrenal Glands
- 1 March 1967
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 80 (3), 521-526
- https://doi.org/10.1210/endo-80-3-521
Abstract
Incorporation of precursors into rat adrenal protein and RNA was inhibited in vitro by ACTH. No inhibition occurred in the presence of agents which interfered with steroidogenesis. Corticosterone, at concentrations comparable to those produced in response to ACTH, likewise caused inhibition of precursor incorporation into RNA and protein of rat adrenal glands. It is thought that the inhibitory effects of ACTH are mediated by the corticosterone it produces.This publication has 3 references indexed in Scilit:
- Further Observations on the Inhibition of Adrenal Protein Synthesis by ACTHin VitroEndocrinology, 1965
- Inhibitionin Vitroof Adrenal Pregnenolone Biosynthesis by Amphenone and Its AnaloguesEndocrinology, 1964
- Effect of Adrenocorticotrophin on Adrenal Protein Synthesis1Endocrinology, 1963