Risk Factors for Meningiomas in Men in Los Angeles County2

Abstract

A case-control study among men in Los Angeles County was conducted to investigate further the causes of intracranial meningiomas. Meningioma patients and a neighbor of each one were interviewed about past experiences that might be associated with tumor development. Analysis of information from the 105 matched pairs showed an association with meningioma occurrence for various factors relating to head trauma and head X-rays: 1) ever boxed as a sport [odds ratio (OR)=2.0, P=0.03], 2) had a serious head injury (OR = 1.9, P=0.01), and 3) had X-ray treatment to the head before 20 years of age and/or had five or more full mouth dental X-ray series before 1945 (OR=3.5, P=0.02). Of the 105 subjects, 72 (69%) had a history of exposure to at least one of these factors.