BILIARY METABOLITES OF 2,5,2',5'-TETRACHLOROBIPHENYL IN RAT

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 14 (3), 527-533
Abstract
Biliary metabolites of rats receiving 3H labeled 2,5,2'',5''-tetrachlorobiphenyl, a component of commercial polychlorinated biphenyl (PCB) mixtures, include 3-OH-2,5,2'',5''-tetrachlorobiphenyl and a dihydrodiol tentatively identified as trans-3,4-dihydrodihydroxy-2,5,2'',5''-tetrachlorobiphenyl. Metabolism of PCBs in the rat probably occurs in part through an arene oxide intermediate. [PCBs are environmental pollutants.].

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