Evaluation of anxiolytic activity of spray dried powders of two South Brazilian Passiflora species
- 18 April 2006
- journal article
- research article
- Published by Wiley in Phytotherapy Research
- Vol. 20 (5), 348-351
- https://doi.org/10.1002/ptr.1853
Abstract
The Passiflora extracts have been used in folk medicine because of its reputed sedative and anxiolytic properties. The present study aimed to compare the potential anxiolytic activity of two Passiflora spray-dried powders obtained from P. alata and P. edulis, known in Brazil as ‘maracujá’. Male adult Swiss rats were treated with 200, 400 and 800 mg/kg of spray-dried powders p.o. and anxiolytic activity was evaluated using the elevated plus-maze test. The spray-dried powders showed anxiolytic activity in doses of 400 and 800 mg/kg. Our results support the potential anxiolytic effect of Passiflora spray-dried powders (P. alata and P. edulis). Copyright © 2006 John Wiley & Sons, Ltd.Keywords
This publication has 24 references indexed in Scilit:
- TLC Fingerprint of Flavonoids and Saponins from Passiflora SpeciesJournal of Liquid Chromatography & Related Technologies, 2005
- Assay of quadranguloside, the major saponin of leaves of Passiflora alata, by HPLC‐UVPhytochemical Analysis, 2004
- Comparative pharmacological study of hydroethanol extracts of Passiflora alata and Passiflora edulis leaves†Phytotherapy Research, 2001
- Steroidal and triterpenoidal glucosides from Passiflora alataJournal of the Brazilian Chemical Society, 2001
- New Cycloartane Triterpenoids from Passiflora edulisJournal of Natural Products, 2000
- The Adjuvants Aerosil 200 and Gelita-Sol-P Influence on the Technological Characteristics of Spray-Dried Powders fromPassiflora edulisvar.flavicarpaDrug Development and Industrial Pharmacy, 2000
- Studies on the Anxiolytic Activity of Eurycoma longifolia Jack Roots in MiceThe Japanese Journal of Pharmacology, 1999
- Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the ratPharmacology Biochemistry and Behavior, 1986
- Selection of Plants for Phytopharmacological Study Based on Modern Herbal PracticeInternational Journal of Crude Drug Research, 1986
- C-Glycosylflavonoids From Passiflora pittieri, P. alata, P., ambigua and Adenia manniiJournal of Natural Products, 1982