Polymorphism of the long-wavelength cone in normal human colour vision
- 1 October 1986
- journal article
- Published by Springer Nature in Nature
- Vol. 323 (6089), 623-625
- https://doi.org/10.1038/323623a0
Abstract
Colour vision is based on the presence of multiple classes of cone each of which contains a different type of photopigment. Colour matching tests have long revealed that the normal human has three cone types. Results from these tests have also been used to provide estimates of cone spectral sensitivities. There are significant variations in colour matches made by individuals whose colour vision is classified as normal. Some of this is due to individual differences in preretinal absorption and photopigment density, but some is also believed to arise because there is variation in the spectral positioning of the cone pigments among those who have normal colour vision. We have used a sensitive colour matching test to examine the magnitude and nature of this individual variation and here report evidence for the existence of two different long-wavelength cone mechanisms in normal humans. The different patterns of colour matches made by male and female subjects indicate these two mechanisms are inherited as an X-chromosome linked trait.Keywords
This publication has 11 references indexed in Scilit:
- Cone mechanisms underlying the color discrimination of deutan color deficientsVision Research, 1985
- Spectral sensitivity of single cones in the retina of Macaca fascicularisNature, 1984
- Homogeneity of large-field color matches in congenital red–green color deficientsJournal of the Optical Society of America, 1982
- Polynomial expressions of pigment nomogramsVision Research, 1981
- Flicker photometric study of chromatic adaptation: selective suppression of cone inputs by colored backgroundsJournal of the Optical Society of America, 1981
- Variability of color mixture data—I. Interobserver variability in the unit coordinatesVision Research, 1976
- Spectral transmission of the human ocular mediaVision Research, 1974
- Light absorption and scatter in the human lensVision Research, 1971
- A cone pigment in the protanopeThe Journal of Physiology, 1963
- The Variation with Age of the Spectral Transmissivity of the Living Human Crystalline LensGerontology, 1959