VibD and VibH Are Required for Late Steps in Vibriobactin Biosynthesis in Vibrio cholerae
- 1 March 2001
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 183 (5), 1830-4
- https://doi.org/10.1128/jb.183.5.1830-1834.2001
Abstract
Vibrio cholerae synthesizes the catechol siderophore vibriobactin. In this report, we present the complete map of a vibriobactin gene region containing two previously unreported vibriobactin biosynthetic genes. vibD encodes a phosphopantetheinyl transferase, and vibH encodes a novel nonribosomal peptide synthase. Both VibD and VibH are required for vibriobactin biosynthesis.Keywords
This publication has 40 references indexed in Scilit:
- Reconstitution and Characterization of the Escherichia coli Enterobactin Synthetase from EntB, EntE, and EntFBiochemistry, 1998
- Enterobactin Biosynthesis in Escherichia coli: Isochorismate Lyase (EntB) Is a Bifunctional Enzyme That Is Phosphopantetheinylated by EntD and Then Acylated by EntE Using ATP and 2,3-DihydroxybenzoateBiochemistry, 1997
- A new enzyme superfamily — the phosphopantetheinyl transferasesChemistry & Biology, 1996
- Cloning and characterization of the Vibrio cholerae genes encoding the utilization of iron from haemin and haemoglobinMolecular Microbiology, 1993
- Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheineBiochemistry, 1991
- Further study on polyamine compositions in VibrionaceaeCanadian Journal of Microbiology, 1991
- Basic local alignment search toolJournal of Molecular Biology, 1990
- The Escherichia coli enterobactin biosynthesis gene, entD: nucleotide sequence and membrane localization of its protein productMolecular Microbiology, 1989
- Polyamine distribution in Vibrionaceae: norspermidine as a general constituent of Vibrio speciesCanadian Journal of Microbiology, 1983
- Studies on transformation of Escherichia coli with plasmidsJournal of Molecular Biology, 1983