The use of fresh and frozen semen in human artificial insemination

Abstract

Summary In a medical practice in which artificial insemination has been carried out for over 40 years, 40% of women inseminated with donor semen (AID), and 21% inseminated with homologous semen (AIH) gave birth to children. Up to December 1975, 399 pregnancies were achieved using fresh donor semen and nineteen with deep-frozen semen. There was no apparent increase in the incidence of birth anomalies in children conceived with frozen semen, nor was there a significant increase in the incidence of still-births, ectopic pregnancy or miscarriage when compared to the rate in the normal population. Eight conceptions were achieved using deep-frozen semen stored for 6 months or longer, and one pregnancy was achieved with a specimen frozen for 3 years. Good cryosurvial was observed in semen frozen for up to 6·7 years. The development of many of the children was followed, and it was concluded that the great majority of marriages into which AID children were born, were undoubtedly enriched and psychological and sociological problems were few. The whole field still awaits the implementation of recommendations concerning the legal status of children born as a result of AID.