An Enzymatic System for Removing Heparin in Extracorporeal Therapy
- 16 July 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4556), 261-263
- https://doi.org/10.1126/science.7089564
Abstract
The need to fully heparinize patients undergoing extracorporeal therapy often leads to hemorrhagic complications. To enable heparinization of only the extracorporeal circuit, a blood filter containing immobilized heparinase was developed. This filter degraded 99 percent of heparin's anticoagulant activity within minutes in both canine and human blood.This publication has 16 references indexed in Scilit:
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