Duchenne muscular dystrophy.
Open Access
- 1 February 1984
- journal article
- Published by BMJ in Journal of Medical Genetics
- Vol. 21 (1), 77
- https://doi.org/10.1136/jmg.21.1.77
Abstract
A segregation analysis on 135 Duchenne families from Venetia (Italy) suggests that the proportion of sporadic cases might be less than expected. Support for this view is also given by an analysis of a pooled sample including 284 additional sibships from comparable studies published previously. Several hypotheses were tested: the maximum likelihood was obtained for a segregation frequency p=0.46 and for a proportion of sporadic cases x=0.227±0.048.Keywords
This publication has 3 references indexed in Scilit:
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- ESTIMATES OF THE SEX RATIO OF MUTATION RATES IN SEX-LINKED CONDITIONS BY THE METHOD OF MAXIMUM LIKELIHOODAnnals of Human Genetics, 1958
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