The oral clearance of zinc and triclosan after delivery from a dentifrice
- 1 June 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 39 (6), 480-483
- https://doi.org/10.1111/j.2042-7158.1987.tb03425.x
Abstract
Oral delivery and retention of zinc and triclosan were measured in man after use of an anti-plaque dentifrice containing these antibacterial agents. Triclosan (25% of the dose) and zinc (24%) were retained in the mouth immediately after toothbrushing and a single mouthrinse. Salivary concentrations fell from 7ṁ5 μg g−1 (triclosan) and 7ṁ0 μg g−1 (zinc) after 5 min to 0ṁ5 μg g−1 (triclosan) and 1ṁ2 μg g−1 (zinc), 2 h after brushing.This publication has 10 references indexed in Scilit:
- The Effects of a Dentifrice Containing Zinc Citrate and 2,4,4' Trichloro‐2'‐Hydroxydiphenyl EtherThe Journal of Periodontology, 1986
- The effect of dentifrices containing zinc citrate on plaque growth and oral zinc levelsJournal of Clinical Periodontology, 1986
- Human oral retention of zinc from mouthwashes containing zinc salts and its relevance to dental plaque controlArchives of Oral Biology, 1984
- Retention of Cu and Zn in the oral cavity following rinsing with aqueous solutions of copper and zinc saltsEuropean Journal of Oral Sciences, 1983
- Chemical inhibition of PlaqueJournal of Clinical Periodontology, 1980
- A comparison between chlorhexidine and some quaternary ammonium compounds with regard to retention, salivary concentration and plaque-inhibiting effect in the human mouth after mouth rinsesArchives of Oral Biology, 1978
- Influence of teeth, plaque and dentures on the retention of chlorhexidine in the human oral cavityJournal of Clinical Periodontology, 1974
- Relationship between plaque-inhibiting effect and retention of chlorhexidine in the human oral cavityArchives of Oral Biology, 1974
- Influence of concentration, time, temperature and pH on the retention of chlorhexidine in the human oral cavity after mouth rinsesArchives of Oral Biology, 1974
- The Pharmacokinetics of Fluoride in Mouth Rinses as Indicated by a Reference Substance (51Cr-EDTA)Caries Research, 1972