Neural control in human muscle fatigue: changes in muscle afferents, moto neurones and moto cortical drive
- 1 February 1998
- journal article
- review article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 162 (3), 275-283
- https://doi.org/10.1046/j.1365-201x.1998.0299f.x
Abstract
To understand the neural factors which contribute to fatigue, it is not satisfactory to regard fatigue as occurring only when a task can no longer be performed. Changes in muscle afferent feedback, moto neuronal discharge, moto cortical output, and perceived effort develop well before an endurance limit in limb muscles. During sustained maximal contractions the discharge of moto neurones declines, commonly to below the level required to produce maximal force from the muscle whose contractile speed is usually slowed. Thus, some `central' fatigue develops. Recent findings using transcranial stimulation have revealed that the moto cortex is one site at which suboptimal output develops during human muscle fatigue. There is a need to study the reflex effects on moto neurones and the excitability of the moto cortex in experimental animals, as well as to apply rigorous methods to assess these processes in voluntary exercise in human subjects.Keywords
This publication has 84 references indexed in Scilit:
- Recurrent inhibition of soleus α-motoneurons during a sustained submaximal plantar flexionElectroencephalography and Clinical Neurophysiology/Electromyography and Motor Control, 1996
- Cerebrospinal fluid dynorphin-converting enzyme activity is increased by voluntary exercise in the spontaneously hypertensive ratLife Sciences, 1993
- Reduced voluntary drive to breathe in asthmatic subjectsRespiration Physiology, 1993
- Neuromodulation of vertebrate motor neuron membrane propertiesCurrent Opinion in Neurobiology, 1992
- Recovery from fatigue of human diaphragm and limb musclesRespiration Physiology, 1991
- VOLUNTARY ACTIVATION OF HUMAN MOTOR AXONS IN THE ABSENCE OF MUSCLE AFFERENT FEEDBACKBrain, 1990
- RESPONSE PROFILES OF HUMAN MUSCLE: AFFERENTS DURING ACTIVE FINGER MOVEMENTSBrain, 1990
- Distribution of recurrent inhibition within a motor nucleus. I. Contribution from slow and fast motor units to the excitation of Renshaw cellsActa Physiologica Scandinavica, 1988
- Changes in human α-motoneuron excitability during sustained maximum isometric contractionsNeuroscience Letters, 1986
- Time course and properties of late adaptation in spinal motoneurones of the catExperimental Brain Research, 1982