Antiphospholipid Antibodies and Pregnancy

Abstract

To the Editor: The paper by Lockshin et al. (July 18 issue)¹ on the presence of anticardiolipin antibody and the outcome of pregnancy in women with systemic lupus erythematosus raises important issues. The association between anticardiolipin antibody and another antiphospholipid antibody in pregnancy, the lupus anticoagulant, is well established.² Retrospective studies have confirmed repeated fetal losses in women with the lupus anticoagulant. We briefly report on our prospective study in 18 women with the lupus anticoagulant; detailed data about 12 of the women have already been published.³ Over the period 1980 to 1985, women at our hospital with known or . . .