The Non-surgical Treatment of Peyronie's Disease

Abstract

Forty-five patients with Peyronie''s disease are described. No patient received treatment for 1 yr from the time of presentation. Three had a complete resolution of their symptoms and signs during this period. The remaining patients received injections of triamcinolone hexacetonide into the plaques at 6-wk intervals for 36 wk. Thirty-three percent had complete or marked improvement in their symptoms; those responding were younger patients with small, firm, discrete plaques in the distal penis. A non-operative approach is recommended in this group. Surgery or chemotherapy should be reserved for those older patients with harder, larger or confluent plaques.