Characterization of the equine influenza virus H 3 with monoclonal antibodies

Abstract
Mouse monoclonal antibodies specific for the hemagglutinin of the prototype equine-2 virus, A/equine/Miami/1/63 (H 3, N 8) demonstrated two related antigenic sites on the H 3. One of the sites was detected on 14 H 3 viruses isolated over a 22 year period (1963–1985). Variant viruses were selected with these antibodies at frequencies similar to those decribed for H 3 hemagglutinins from human isolates.