SPECIFIC BINDING OF LEUCYL TRANSFER RNA TO AN IMMATURE FORM OF L-THREONINE DEAMINASE: ITS IMPLICATIONS IN REPRESSION
- 1 August 1970
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 66 (4), 1027-1035
- https://doi.org/10.1073/pnas.66.4.1027
Abstract
The in vitro assembly of L-threonine deaminase from its constituent parts results in the formation of an inactive species of this enzyme which specifically and reversibly binds leucyl-tRNA. The native, catalytically active enzyme, which is derived from this species in the presence of maturation-inducing ligands, does not bind tRNA. The possible involvement of this protein-tRNA complex in the repression of the ilv (ADE) operon is discussed.Keywords
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