Target Flexibility: An Emerging Consideration in Drug Discovery and Design
Top Cited Papers
- 12 September 2008
- journal article
- review article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 51 (20), 6237-6255
- https://doi.org/10.1021/jm800562d
Abstract
No abstract availableKeywords
This publication has 158 references indexed in Scilit:
- Flexible ligand docking to multiple receptor conformations: a practical alternativeCurrent Opinion in Structural Biology, 2008
- A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE)Journal of Computer-Aided Molecular Design, 2008
- Dynamic personalities of proteinsNature, 2007
- Intrinsic dynamics of enzymes in the unbound state and relation to allosteric regulationCurrent Opinion in Structural Biology, 2007
- Intrinsic dynamics of an enzyme underlies catalysisNature, 2005
- Scalable molecular dynamics with NAMDJournal of Computational Chemistry, 2005
- GROMACS: Fast, flexible, and freeJournal of Computational Chemistry, 2005
- Improved protein–ligand docking using GOLDProteins-Structure Function and Bioinformatics, 2003
- Seven-transmembrane receptorsNature Reviews Molecular Cell Biology, 2002
- CHARMM: A program for macromolecular energy, minimization, and dynamics calculationsJournal of Computational Chemistry, 1983